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Multiple distinct evolutionary mechanisms govern the dynamics of selfish mitochondrial genomes in Caenorhabditis elegans

Abstract Cells possess multiple mitochondrial DNA (mtDNA) copies, which undergo semi-autonomous replication and stochastic inheritance. This enables mutant mtDNA variants to arise and selfishly compete with cooperative (wildtype) mtDNA. Selfish mitochondrial genomes are subject to selection at diffe...

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Bibliografiska uppgifter
Huvudupphov: Bryan L. Gitschlag, Claudia V. Pereira, James P. Held, David M. McCandlish, Maulik R. Patel
Materialtyp: Artigo
Språk:Inglês
Utgiven: Nature Portfolio 2024-09-01
Serie:Nature Communications
Länkar:https://doi.org/10.1038/s41467-024-52596-9
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