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Exosomes from tubular epithelial cells undergoing epithelial‐to‐mesenchymal transition promote renal fibrosis by M1 macrophage activation

Abstract Kidney fibrosis is the common final pathway of chronic kidney disease (CKD), and it is distinguished by inflammation, mesenchymal transition with myofibroblast formation, and epithelial‐to‐mesenchymal transition (EMT). Macrophages are protuberant inflammatory cells in the kidney, and their...

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Bibliografiske detaljer
Principais autores: Yuqing Lu, Rui Zhang, Xiameng Gu, Xuerong Wang, Peipei Xi, Xiaolan Chen
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2023-03-01
Serier:FASEB BioAdvances
Fag:
Online adgang:https://doi.org/10.1096/fba.2022-00080
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