A circuit for secretion‐coupled cellular autonomy in multicellular eukaryotic cells

Abstract Cancers represent complex autonomous systems, displaying self‐sufficiency in growth signaling. Autonomous growth is fueled by a cancer cell's ability to “secrete‐and‐sense” growth factors (GFs): a poorly understood phenomenon. Using an integrated computational and experimental approach, her...

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Principais autores:	Lingxia Qiao, Saptarshi Sinha, Amer Ali Abd El‐Hafeez, I‐Chung Lo, Krishna K Midde, Tony Ngo, Nicolas Aznar, Inmaculada Lopez‐Sanchez, Vijay Gupta, Marilyn G Farquhar, Padmini Rangamani, Pradipta Ghosh
Format:	Artigo
Jezik:	Inglês
Izdano:	Springer Nature 2023-03-01
Serija:	Molecular Systems Biology
Teme:	cellular autonomy dose–response alignment (DoRA) epidermal growth factor receptor (EGFR) G proteins Golgi secretion
Online dostop:	https://doi.org/10.15252/msb.202211127
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