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Radiosensitization Effect of Gold Nanoparticles on Plasmid DNA Damage Induced by Therapeutic MV X-rays

Gold nanoparticles (AuNPs) can be used with megavolt (MV) X-rays to exert radiosensitization effects, as demonstrated in cell survival assays and mouse experiments. However, the detailed mechanisms are not clear; besides physical dose enhancement, several chemical and biological processes have been...

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Principais autores: Katsunori Yogo, Masaki Misawa, Hidetoshi Shimizu, Tomoki Kitagawa, Ryoichi Hirayama, Hiromichi Ishiyama, Hiroshi Yasuda, Satoshi Kametaka, Seiichi Takami
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-02-01
coleção:Nanomaterials
Assuntos:
gold nanoparticle
radiation therapy
DNA damage
radiosensitizer
MV X-rays
positively charged nanoparticle
Acesso em linha:https://www.mdpi.com/2079-4991/12/5/771
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