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The ER Stress/UPR Axis in Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis

Cellular protein homeostasis in the lungs is constantly disrupted by recurrent exposure to various external and internal stressors, which may cause considerable protein secretion pressure on the endoplasmic reticulum (ER), resulting in the survival and differentiation of these cell types to meet the...

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Principais autores: Mahmoud Aghaei, Sanaz Dastghaib, Sajjad Aftabi, Mohamad-Reza Aghanoori, Javad Alizadeh, Pooneh Mokarram, Parvaneh Mehrbod, Milad Ashrafizadeh, Ali Zarrabi, Kielan Darcy McAlinden, Mathew Suji Eapen, Sukhwinder Singh Sohal, Pawan Sharma, Amir A. Zeki, Saeid Ghavami
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-12-01
coleção:Life
Assuntos:
endoplasmic reticulum
fibrosis
tissue remodeling
non-coding RNA
UPR
autophagy
Acesso em linha:https://www.mdpi.com/2075-1729/11/1/1
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