Asciminib and pulsed ATRA as post-remission therapy in T315I mutated PML-RARA-positive blast crisis of chronic myeloid leukemia

Abstract Promyelocytic blast crisis (BC) of CML is an extremely rare event, with only seven cases described as arising during therapy with TKIs. We present a 68-year-old male who developed promyelocytic blast crisis 12 months after CML diagnosis and start of Imatinib therapy, confirmed by the concom...

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Detalhes bibliográficos

Principais autores:	Roberta Mazzarella, Laura Cicconi, Salvatore Perrone, Maria Domenica Divona, Sara Ceccolini, Anna Maria Nardozza, Annalisa Biagi, Tiziana Ottone, Andrea Corbingi, Paola Panetta, Elettra Ortu La Barbera, Luciano Fiori, Azzurra Anna Romeo, Giada Pacitto, Ettore Cotroneo, Massimo Breccia, Maria Teresa Voso, Alessandro Pulsoni
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer 2026-02-01
coleção:	Annals of Hematology
Assuntos:	CML Blast crisis Asciminib T315I PML-RARA
Acesso em linha:	https://doi.org/10.1007/s00277-026-06793-9
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