Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome

Abstract Hutchinson-Gilford progeria syndrome (HGPS) and Werner syndrome (WS) are two of the best characterized human progeroid syndromes. HGPS is caused by a point mutation in lamin A (LMNA) gene, resulting in the production of a truncated protein product—progerin. WS is caused by mutations in WRN...

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Auteurs principaux:	Zeming Wu, Weiqi Zhang, Moshi Song, Wei Wang, Gang Wei, Wei Li, Jinghui Lei, Yu Huang, Yanmei Sang, Piu Chan, Chang Chen, Jing Qu, Keiichiro Suzuki, Juan Carlos Izpisua Belmonte, Guang-Hui Liu
Format:	Artigo
Langue:	Inglês
Publié:	Oxford University Press 2018-02-01
Collection:	Protein & Cell
Sujets:	WRN lamin HGPS Werner syndrome stem cell aging
Accès en ligne:	http://link.springer.com/article/10.1007/s13238-018-0517-8
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