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Low-dose valine attenuates diet-induced metabolic dysfunction-associated steatotic liver disease (MASLD) in mice by enhancing leptin sensitivity and modulating the gut microbiome

Objectives: Elevated circulating branched-chain amino acids (BCAAs) have been associated with obesity, insulin resistance, and MASLD. Nonetheless, BCAA supplementation has been shown to provide protective outcomes towards the intervention of MASLD. Currently, there is a lack of study towards the con...

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Principais autores: Felicianna, Emily K.K. Lo, Congjia Chen, Marsena J. Ismaiah, Fangfei Zhang, Hoi Kit Matthew Leung, Hani El-Nezami
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-12-01
Serier:Molecular Metabolism
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Online adgang:http://www.sciencedirect.com/science/article/pii/S221287782400190X
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