Cytochromes P450 from family 4 are the main omega hydroxylating enzymes in humans: CYP4F3B is the prominent player in PUFA metabolism1

Human CYP450 ω-hydroxylases of the CYP4 family are known to convert arachidonic acid (AA) to its metabolite 20-hydroxyeicosatetraenoic acid (20-HETE). This study deals with hydroxylations of four PUFAs, eicosatrienoic acid (ETA), AA, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) by eit...

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Autors principals:	Maude Fer, Laurent Corcos, Yvonne Dréano, Emmanuelle Plée-Gautier, Jean-Pierre Salaün, François Berthou, Yolande Amet
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2008-11-01
Col·lecció:	Journal of Lipid Research
Matèries:	ω-hydroxylation (ω-1)-hydroxylation inhibition
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S0022227520346150
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