Mutation Analysis in the Coding Sequence of Thymidine Kinase 1 in Breast and Colorectal Cancer
We report the first mutational study of thymidine kinase 1 (TK1) performed in human solid tumors. We sequenced cDNAs representing the complete coding region of TK1 in human breast (n=22) and colorectal (n=26) cancer. Codon 106 near the ATP binding site constantly differed (ATG → G TG; Met → Val ) fr...
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| Principais autores: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publishing
2003-01-01
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| coleção: | The International Journal of Biological Markers |
| Acesso em linha: | https://doi.org/10.1177/172460080301800101 |
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