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SAFlex: A structural alphabet extension to integrate protein structural flexibility and missing data information.

In this paper, we describe SAFlex (Structural Alphabet Flexibility), an extension of an existing structural alphabet (HMM-SA), to better explore increasing protein three dimensional structure information by encoding conformations of proteins in case of missing residues or uncertainties. An SA aims t...

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Autores principales: Ikram Allam, Delphine Flatters, Géraldine Caumes, Leslie Regad, Vincent Delos, Gregory Nuel, Anne-Claude Camproux
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2018-01-01
Colección:PLoS ONE
Acceso en línea:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0198854&type=printable
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