Swiprosin-1 Promotes Mitochondria-Dependent Apoptosis of Glomerular Podocytes via P38 MAPK Pathway in Early-Stage Diabetic Nephropathy

Background/Aims: Podocyte injury, especially podocyte apoptosis, plays a major role in early-stage diabetic nephropathy (DN). Swiprosin-1, also known as EF hand domain containing 2 (EFhd2), is a Ca2+-binding protein in different cell types. However, the function of swiprosin-1 in podocytes remains u...

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Principais autores:	Rong-Mei Wang, Zhi-Bin Wang, Yue Wang, Wei-Ye Liu, Ya Li, Ling-Chang Tong, Su Zhang, Ding-Feng Su, Yong-Bing Cao, Ling Li, Li-Chao Zhang
格式:	Artigo
语言:	Inglês
出版:	Cell Physiol Biochem Press GmbH & Co KG 2018-02-01
丛编:	Cellular Physiology and Biochemistry
主题:	Diabetic nephropathy Podocyte Apoptosis Swiprosin-1 P38 MAPK
在线阅读:	https://www.karger.com/Article/FullText/487285
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