A novel function of STAT3β in suppressing interferon response improves outcome in acute myeloid leukemia

Abstract Signal transducer and activator of transcription 3 (STAT3) is frequently overexpressed in patients with acute myeloid leukemia (AML). STAT3 exists in two distinct alternatively spliced isoforms, the full-length isoform STAT3α and the C-terminally truncated isoform STAT3β. While STAT3α is pr...

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Autori principali:	Sophie Edtmayer, Agnieszka Witalisz-Siepracka, Bernhard Zdársky, Kerstin Heindl, Stefanie Weiss, Thomas Eder, Sayantanee Dutta, Uwe Graichen, Sascha Klee, Omar Sharif, Rotraud Wieser, Balázs Győrffy, Valeria Poli, Emilio Casanova, Heinz Sill, Florian Grebien, Dagmar Stoiber
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2024-05-01
Serie:	Cell Death and Disease
Accesso online:	https://doi.org/10.1038/s41419-024-06749-9
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