क्यूआर कोड

Protein Quality Control Activation and Microtubule Remodeling in Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disorder. It is mainly caused by mutations in genes encoding sarcomere proteins. Mutant forms of these highly abundant proteins likely stress the protein quality control (PQC) system of cardiomyocytes. The PQC system, together wi...

पूर्ण विवरण

में बचाया:
मुख्य लेखकों: Larissa M. Dorsch, Maike Schuldt, Cristobal G. dos Remedios, Arend F. L. Schinkel, Peter L. de Jong, Michelle Michels, Diederik W. D. Kuster, Bianca J. J. M. Brundel, Jolanda van der Velden
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI AG 2019-07-01
श्रृंखला:Cells
विषय:
cardiomyopathy
hypertrophy
sarcomere mutation
haploinsufficiency
poison polypeptide
protein quality control
heat shock proteins
autophagy
microtubules
ऑनलाइन पहुंच:https://www.mdpi.com/2073-4409/8/7/741
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