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Mast cell degranulation and bradykinin-induced angioedema - searching for the missing link

Initiation of the bradykinin generation cascade is responsible for the occurrence of attacks in some types of angioedema without wheals. Hereditary angioedema due to C1 inhibitor deficiency (HAE-C1-INH) is one such clinical entity. In this paper, we explore the existing evidence that mast cells (MCs...

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Principais autores: Grzegorz Porebski, Alicja Dziadowiec, Hubert Rybka, Radoslaw Kitel, Mateusz Kwitniewski
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2024-05-01
סדרה:Frontiers in Immunology
נושאים:
bradykinin
C1 inhibitor deficiency
HAE
hereditary angioedema
mast cell
MRGPRX2
גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1399459/full
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