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Ultrasound-Sensitive Liposomal Exatecan for Tumor-Specific Drug Release for Treatment of Pancreatic Cancer

<b>Background:</b> Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal cancers, largely due to its dense stromal architecture and poor intratumoral drug penetration. To address this challenge, IMP305 was developed as an ultrasound-sensitive liposome for tumor-localized drug releas...

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Principais autores: Dongyeon Kim, Hyungwon Moon, Sunyoung Han, Hak Jong Lee
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2025-12-01
coleção:Pharmaceutics
Assuntos:
exatecan mesylate
ultrasound-sensitive liposome
focused ultrasound
pancreatic cancer
nanomedicine
tumor-targeted chemotherapy
Acesso em linha:https://www.mdpi.com/1999-4923/18/1/3
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