Monocyte-macrophage SAMHD1 alleviates EAMG by modulating the cGAS-STING pathway

Abstract Background Myasthenia gravis (MG) is an autoimmune disorder whose pathogenesis has not been fully elucidated but is primarily associated with immune system dysregulation. Growing evidence indicates that innate immunity mediated by monocyte-macrophages plays a significant role in the pathoge...

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Detalhes bibliográficos

Principais autores:	Wenjun Que, Rui Fan, Dan Lu, Linqi Liu, Jing Dong, Pingyang Ke, Sisi Jing, Yaoqi Gan, Fei Xiao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-02-01
coleção:	Journal of Neuroinflammation
Assuntos:	SAMHD1 Myasthenia gravis cGAS-STING Monocyte-macrophage Innate immunity
Acesso em linha:	https://doi.org/10.1186/s12974-026-03747-w
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