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A GMP-compliant manufacturing method for Wharton’s jelly-derived mesenchymal stromal cells

Abstract Background Wharton’s jelly-derived mesenchymal stem cells (WJ-MSCs) hold great therapeutic potential in regenerative medicine. Therefore, it is crucial to establish a Good Manufacturing Practice (GMP)-compliant methodology for the isolation and culture of WJ-MSCs. Through comprehensive rese...

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Main Authors: Wanglong Chu, Fen Zhang, Xiuping Zeng, Fangtao He, Guanyan Shang, Tao Guo, Qingfang Wang, Jianfu Wu, Tongjing Li, Zhen Zhong Zhong, Xiao Liang, Junyuan Hu, Muyun Liu
Format: Artigo
Language:Inglês
Published: BMC 2024-05-01
Series:Stem Cell Research & Therapy
Subjects:
Enzymatic digestion
Good manufacturing practice
Mesenchymal stem cells
Scale-up
Stability
Wharton jelly
Online Access:https://doi.org/10.1186/s13287-024-03725-0
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