Determinants of HIV-1 reservoir size and long-term dynamics during suppressive ART

Here, Bachmann et al. provide data on long-term dynamics of the HIV-1 reservoir in 1,057 individuals on suppressive antiretroviral therapy and show that in 26.6% of individuals the reservoir increases. Viral blips and low-level viremia are significantly associated with a slower reservoir decay.

Dades bibliogràfiques

Autors principals:	Nadine Bachmann, Chantal von Siebenthal, Valentina Vongrad, Teja Turk, Kathrin Neumann, Niko Beerenwinkel, Jasmina Bogojeska, Jaques Fellay, Volker Roth, Yik Lim Kok, Christian W. Thorball, Alessandro Borghesi, Sonali Parbhoo, Mario Wieser, Jürg Böni, Matthieu Perreau, Thomas Klimkait, Sabine Yerly, Manuel Battegay, Andri Rauch, Matthias Hoffmann, Enos Bernasconi, Matthias Cavassini, Roger D. Kouyos, Huldrych F. Günthard, Karin J. Metzner, the Swiss HIV Cohort Study
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2019-07-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-019-10884-9
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