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Potential effects of allyl isothiocyanate on inhibiting cellular proliferation and inducing apoptotic pathway in human cisplatin-resistant oral cancer cells

Background/purpose: Cisplatin-resistant oral cancer is clinically difficult to manage and the dose-dependent toxicities of cisplatin has been widely concerned. Allyl isothiocyanate (AITC), known as mustard oil, is a plant-derived compound abundant in cruciferous vegetables. It is reported to have an...

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Principais autores: Pei-ying Chang, Fuu-jen Tsai, Da-tian Bau, Yuan-man Hsu, Jai-sing Yang, Ming-gene Tu, Shang-lun Chiang
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021-01-01
Serier:Journal of the Formosan Medical Association
Fag:
AITC
Apoptosis
CAR cells
Cisplatin resistance
OSCC
Online adgang:http://www.sciencedirect.com/science/article/pii/S0929664620302850
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