Synergistic inhibition of tumor growth by combination treatment with drugs against different subpopulations of glioblastoma cells

Abstract Background Glioma stem cells (GSCs) contribute to tumor recurrence and drug resistance. This study characterizes the tumorigenesis of CD133+ cells and their sensitivity to pharmacological inhibition. Methods GSCs from human U87 and rat C6 glioblastoma cell lines were isolated via magnetic c...

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Bibliografische gegevens

Hoofdauteurs:	Chia-Hsin Chang, Wei-Ting Liu, Hui-Chi Hung, Chia-Yu Gean, Hong-Ming Tsai, Chun-Lin Su, Po-Wu Gean
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	BMC 2017-12-01
Reeks:	BMC Cancer
Onderwerpen:	Glioma Cancer stem cells Minocycline STAT3 Combination therapy Synergy
Online toegang:	http://link.springer.com/article/10.1186/s12885-017-3924-y
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