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Metabolic control analysis of respiration in human cancer tissue

Bioenergetic profiling of cancer cells is of great potential because it can bring forward new and effective therapeutic strategies along with early diagnosis. Metabolic Control Analysis (MCA) is a methodology that enables quantification of the flux control exerted by different enzymatic steps in a m...

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Autori principali: Tuuli eKaambre, Vladimir eChekulayev, Igor eShevchuk, Kersti eTepp, Natalja eTimohhina, Minna eVarikmaa, Rafaela eBagur, Aleksandr eKlepinin, Tiia eAnmann, Andre eKoit, Andrus eKaldma, Rita eGuzun, Vahur eValvere, Valdur eSaks
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2013-06-01
Serie:Frontiers in Physiology
Soggetti:
breast cancer
colorectal cancer
respiratory chain
Metabolic Control Analysis
Warburg effect
OxPhos
Accesso online:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00151/full
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