An integrated proteomic and glycoproteomic approach uncovers differences in glycosylation occupancy from benign and malignant epithelial ovarian tumors

Abstract Background Epithelial ovarian carcinomas encompass a heterogeneous group of diseases with a poor 5-year survival rate. Serous carcinoma is the most common type. Most FDA-approved serum tumor markers are glycoproteins. These glycoproteins on cell surface or shed into the bloodstream could se...

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Autori principali:	Qing Kay Li, Punit Shah, Yuan Tian, Yingwei Hu, Richard B. S. Roden, Hui Zhang, Daniel W. Chan
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2017-05-01
Serie:	Clinical Proteomics
Soggetti:	Ovarian high-grade serous carcinoma Proteomics Glycoproteomics
Accesso online:	http://link.springer.com/article/10.1186/s12014-017-9152-2
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