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Neurogenesis drives hippocampal formation-wide spatial transcription alterations in health and Alzheimer's disease

The mechanism by which neurogenesis regulates the profile of neurons and glia in the hippocampal formation is not known. Further, the effect of neurogenesis on neuronal vulnerability characterizing the entorhinal cortex in Alzheimer's disease (AD) is unknown. Here, we used in situ sequencing to inve...

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Главные авторы: Zachery D. Morrissey, Pavan Kumar, Trongha X. Phan, Mark Maienschein-Cline, Alex Leow, Orly Lazarov
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2025-04-01
Серии:Frontiers in Dementia
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Online-ссылка:https://www.frontiersin.org/articles/10.3389/frdem.2025.1546433/full
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