CIC reduces xCT/SLC7A11 expression and glutamate release in glioma
Abstract Capicua (CIC) is an important downstream molecule of RTK/RAS/MAPK pathway. The regulatory mechanism of CIC underlying tumorigenesis in oligodendroglioma, where CIC is frequently mutated, has yet to be fully elucidated. Using patient-derived glioma lines, RNA-sequencing and bioinformatic ana...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BMC
2023-01-01
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| Серии: | Acta Neuropathologica Communications |
| Предметы: | |
| Online-ссылка: | https://doi.org/10.1186/s40478-023-01507-y |
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