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The CERV protein of Cer1, a C. elegans LTR retrotransposon, is required for nuclear export of viral genomic RNA and can form giant nuclear rods.

Retroviruses and closely related LTR retrotransposons export full-length, unspliced genomic RNA (gRNA) for packaging into virions and to serve as the mRNA encoding GAG and POL polyproteins. Because gRNA often includes splice acceptor and donor sequences used to splice viral mRNAs, retroelements must...

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Bibliographic Details
Main Authors: Bing Sun, Haram Kim, Craig C Mello, James R Priess
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2023-06-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010804
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