Impact of an additional chronic BDNF reduction on learning performance in an Alzheimer mouse model

There is increasing evidence that brain-derived neurotrophic factor (BDNF) plays a crucial role in AD pathology. A number of studies demonstrated that AD patients exhibit reduced BDNF levels in the brain and the blood serum, and in addition, several animal-based studies indicated a potential protect...

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Bibliografske podrobnosti

Principais autores:	Laura ePsotta, Carolin eRockahr, Michael eGruss, Elmar eKirches, Katharina A Braun, Volkmar eLessmann, Joerg eBock, Thomas eEndres
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2015-03-01
Serija:	Frontiers in Behavioral Neuroscience
Teme:	BDNF object recognition Alzheimer’s disease water maze active avoidance APP/Ps1
Online dostop:	http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00058/full
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