Pro-asthmatic cytokines regulate unliganded and ligand-dependent glucocorticoid receptor signaling in airway smooth muscle.

To elucidate the regulation of glucocorticoid receptor (GR) signaling under pro-asthmatic conditions, cultured human airway smooth muscle (HASM) cells were treated with proinflammatory cytokines or GR ligands alone and in combination, and then examined for induced changes in ligand-dependent and -in...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Aihua Hu, Maureen B Josephson, Barry L Diener, Gustavo Nino, Shuyun Xu, Chinmay Paranjape, Jordan S Orange, Michael M Grunstein
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2013-01-01
coleção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC3617099?pdf=render
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!