Intratumorally delivered formulation, INT230-6, containing potent anticancer agents induces protective T cell immunity and memory

The benefits of anti-cancer agents extend beyond direct tumor killing. One aspect of cell death is the potential to release antigens that initiate adaptive immune responses. Here, a diffusion enhanced formulation, INT230-6, containing potent anti-cancer cytotoxic agents, was administered intratumora...

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Podrobná bibliografie

Hlavní autoři:	Anja C. Bloom, Lewis H. Bender, Shweta Tiwary, Lise Pasquet, Katharine Clark, Tianbo Jiang, Zheng Xia, Aizea Morales-Kastresana, Jennifer C. Jones, Ian Walters, Masaki Terabe, Jay A. Berzofsky
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis Group 2019-10-01
Edice:	OncoImmunology
Témata:	endogenous vaccine tumor model anticancer agent t cells intratumoral delivery pd-1 chemotherapy combination therapy immunogenic cell death
On-line přístup:	http://dx.doi.org/10.1080/2162402X.2019.1625687
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