Polarization of tumor-associated macrophages by TLR7/8 conjugated radiosensitive peptide hydrogel for overcoming tumor radioresistance

Radioresistance reduces the antitumor efficiency of radiotherapy and further restricts its clinical application, which is mainly caused by the aggravation of immunosuppressive tumor microenvironment (ITM). Especially tumor-associated macrophages (TAMs) usually display the tumor-promoting M2 phenotyp...

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Автори:	Yumin Zhang, Zujian Feng, Jinjian Liu, Hui Li, Qi Su, Jiamin Zhang, Pingsheng Huang, Weiwei Wang, Jianfeng Liu
Формат:	Artigo
Мова:	Inglês
Опубліковано:	KeAi Communications Co., Ltd. 2022-10-01
Серія:	Bioactive Materials
Предмети:	Radioresistance Tumor-associated macrophage Polarization Immunosuppressive tumor microenvironment Peptide hydrogel
Онлайн доступ:	http://www.sciencedirect.com/science/article/pii/S2452199X21006071
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