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Nucleoporin 85 interacts with influenza A virus PB1 and PB2 to promote its replication by facilitating nuclear import of ribonucleoprotein

Transcription and replication of the influenza A virus (IAV) genome take place in the nucleus of infected cells, which rely on host factors to aid viral ribonucleoprotein (vRNP) to cross the nuclear pore complex (NPC) and complete the bidirectional nucleocytoplasmic trafficking. Here, we showed that...

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Principais autores: Yue-Huan Ling, Hao Wang, Mei-Qing Han, Di Wang, Yi-Xiang Hu, Kun Zhou, Yan Li
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-08-01
Serier:Frontiers in Microbiology
Fag:
influenza A virus
NUP85
RNP
PB1
PB2
nuclear import
Online adgang:https://www.frontiersin.org/articles/10.3389/fmicb.2022.895779/full
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