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APEX2 and TurboID define unique subcellular proteomes

Abstract Proximity labeling has emerged as a prominent, reliable tool for obtaining local proteomes from a wide range of cell-types. Two major classes of labeling reagents, peroxidase based (APEX family), or biotin-ligase based (BioID family) have been developed in parallel. These two approaches are...

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Bibliographic Details
Main Authors: Alexandria S. Battison, Jeremy L. Balsbaugh, Jeremy C. Borniger
Format: Artigo
Language:Inglês
Published: Nature Portfolio 2025-12-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-27545-1
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