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Caspase 6 promotes innate immune activation by functional crosstalk between RIPK1-IκBα axis in liver inflammation

Abstract Background Caspase 6 is an essential regulator in innate immunity, inflammasome activation and host defense. We aimed to characterize the causal mechanism of Caspase 6 in liver sterile inflammatory injury. Methods Human liver tissues were harvested from patients undergoing ischemia-related...

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Principais autores: Yuanbang Lin, Mingwei Sheng, Hua Qin, Peng Zhang, Chunli Wang, Wei Fu, Xiangjun Meng, Duowei Wang, Yachao Hou
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2023-10-01
Colecção:Cell Communication and Signaling
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Acesso em linha:https://doi.org/10.1186/s12964-023-01287-x
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