DDB2 expression lights the way for precision radiotherapy response in PDAC cells, with or without olaparib

Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers. Therapeutic options for PDAC are primarily restricted to surgery in the early stages of the disease or chemotherapy in advanced disease. Only a subset of patients with germline defects in BRCA1/2 genes can potentially...

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Bibliographic Details

Main Authors:	Julie Dardare, Andréa Witz, Margaux Betz, Aurélie François, Laureline Lamy, Marie Husson, Jessica Demange, Marie Rouyer, Aurélien Lambert, Jean-Louis Merlin, Pauline Gilson, Alexandre Harlé
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 2024-09-01
Series:	Cell Death Discovery
Online Access:	https://doi.org/10.1038/s41420-024-02188-9
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