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Study of the Chemotactic Response of Multicellular Spheroids in a Microfluidic Device.

We report the first application of a microfluidic device to observe chemotactic migration in multicellular spheroids. A microfluidic device was designed comprising a central microchamber and two lateral channels through which reagents can be introduced. Multicellular spheroids were embedded in colla...

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Autors principals: Jose M Ayuso, Haneen A Basheer, Rosa Monge, Pablo Sánchez-Álvarez, Manuel Doblaré, Steven D Shnyder, Victoria Vinader, Kamyar Afarinkia, Luis J Fernández, Ignacio Ochoa
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2015-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC4596573?pdf=render
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