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Paraptosis and NF-κB activation are associated with protopanaxadiol-induced cancer chemoprevention

<p>Abstract</p> <p>Background</p> <p>Protopanaxadiol (PPD) is a triterpenoid that can be prepared from steamed ginseng. PPD possesses anticancer potential via caspase-dependent apoptosis. Whether paraptosis, a type of the caspase-independent cell death, is also induced by PPD has not been evaluated....

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Principais autores: Wang Chong-Zhi, Li Binghui, Wen Xiao-Dong, Zhang Zhiyu, Yu Chunhao, Calway Tyler D, He Tong-Chuan, Du Wei, Yuan Chun-Su
פורמט: Artigo
שפה:Inglês
יצא לאור: BMC 2013-01-01
סדרה:BMC Complementary and Alternative Medicine
נושאים:
Ginseng
Protopanaxadiol
PPD
Paraptosis
Cytoplasmic vacuoles
Mitochondrial swelling
Antioxidant
Cancer chemoprevention
גישה מקוונת:http://www.biomedcentral.com/1472-6882/13/2
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