The Roles of PCSK9 in Alzheimer’s Disease: A Systematic Review of Clinical, Genetic, and Preclinical Evidence
Alzheimer’s disease (AD) is increasingly associated with alterations in cholesterol metabolism. Proprotein convertase subtilisin/kexin type 9 (PCSK9), an enzyme regulating low-density lipoprotein receptor (LDLR) degradation, has been implicated in AD through mechanisms involving amyloid-β (Aβ) proce...
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| Formaat: | Artigo |
| Taal: | Inglês |
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MDPI AG
2025-12-01
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| Reeks: | Life |
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| Online toegang: | https://www.mdpi.com/2075-1729/15/12/1851 |
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