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Mass spectrometry-based proteomics delivers in-depth proteome profiling of FFPE lung cancer biopsies from single glass slides

Abstract Clinical proteomics has the potential to add a valuable data layer to genomic and histopathological analyses in precision oncology, but its application to limited clinical material remains challenging. Here, we demonstrate that state-of-the-art mass spectrometry-based proteomics enables in-...

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Autores principales: Olena Berkovska, Igor Schliemann, Georgios Mermelekas, Nazlı Ezgi Özkan, Mahnaz Nikpour, Vilde Drageset Haakensen, Åslaug Helland, Janne Lehtiö, Lukas M. Orre
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Portfolio 2026-05-01
Colección:npj Precision Oncology
Acceso en línea:https://doi.org/10.1038/s41698-026-01517-8
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