Intra-patient and inter-patient comparisons of DNA damage response biomarkers in Nasopharynx Cancer (NPC): analysis of NCC0901 randomised controlled trial of induction chemotherapy in locally advanced NPC

Abstract Background Inter-patient heterogeneity in radiation-induced DNA damage responses is proposed to reflect intrinsic variations in tumour and normal tissue radiation sensitivity, but the prediction of phenotype by a molecular biomarker is influenced by clinical confounders and assay reproducib...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Kevin Lee Min Chua, Eugenia Li Ling Yeo, Waseem Ahamed Shihabudeen, Sze Huey Tan, Than Than Shwe, Enya Hui Wen Ong, Paula Yeng Po Lam, Khee Chee Soo, Yoke Lim Soong, Kam Weng Fong, Terence Wee Kiat Tan, Joseph Tien Seng Wee, Melvin Lee Kiang Chua
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2018-11-01
coleção:	BMC Cancer
Assuntos:	Radiation-induced apoptosis DNA repair DNA damage response Biomarker Biological heterogeneity
Acesso em linha:	http://link.springer.com/article/10.1186/s12885-018-5005-2
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!