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Candida albicans Filamentation Does Not Require the cAMP-PKA Pathway In Vivo

ABSTRACT Candida albicans is one of the most prevalent human fungal pathogens. Its ability to transition between budding yeast and filamentous morphological forms (pseudohyphae and hyphae) is tightly associated with its pathogenesis. Based on in vitro studies, the cAMP-protein kinase A (PKA) pathway...

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Autori principali: Rohan S. Wakade, Juraj Kramara, Melanie Wellington, Damian J. Krysan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2022-06-01
Serie:mBio
Soggetti:
Candida albicans
fungal pathogenesis
NFAT transcription factors
protein kinase A
cyclic AMP
hyphae
Accesso online:https://journals.asm.org/doi/10.1128/mbio.00851-22
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