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Pharmacogenetics of Metformin Transporters Suggests No Association with Therapeutic Inefficacy among Diabetes Type 2 Mexican Patients

Mexico has been under official epidemiological alert due to diabetes since 2016. This study presents new information on the frequency and variants of metformin transporters OCT1, OCT2, OCT3, <i>ABCB1</i>, and <i>CYP2C9</i> variants as well. It also reports the association with HbA1c control on 103 D...

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Principais autores: Adiel Ortega-Ayala, Nidia Samara Rodríguez-Rivera, Fernando de Andrés, Adrián LLerena, Eliseo Pérez-Silva, Adriana Guadalupe Espinosa-Sánchez, Juan Arcadio Molina-Guarneros
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-06-01
Serier:Pharmaceuticals
Fag:
pharmacogenetics
diabetes type 2
metformin
sulphonylureas
transporters
therapeutic inefficacy
Online adgang:https://www.mdpi.com/1424-8247/15/7/774
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