Development of Capillary Zone Electrophoresis Method for the Simultaneous Separation and Quantification of Metformin and Pioglitazone in Dosage Forms; and Comparison with HPLC Method

A capillary zone electrophoretic (CZE) method was developed, validated, and applied for the assay of metformin (MET) and pioglitazone (PIO) in pharmaceutical formulations. The optimum running buffer composition was found to be 75 mmol/L phosphate buffer containing 30% acetonitrile (ACN) at pH 4.0. T...

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Autori principali:	Maymonah K. I. AlThikrallah, Abubakr M. Idris, Abdalla Ahmed Elbashir, Rafea E. E. Elgorashe, Alyah Buzid, Ahmed O. Alnajjar
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2023-01-01
Serie:	Molecules
Soggetti:	capillary electrophoresis pioglitazone metformin diabetes mellitus pharmaceutical formulations analytical method validation
Accesso online:	https://www.mdpi.com/1420-3049/28/3/1184
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