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A Robust Phenotypic High-Throughput Antiviral Assay for the Discovery of Rabies Virus Inhibitors

Rabies virus (RABV) causes severe neurological symptoms in mammals. The disease is almost inevitably lethal as soon as clinical symptoms appear. The use of rabies immunoglobulins (RIG) and vaccination in post-exposure prophylaxis (PEP) can provide efficient protection, but many people do not receive...

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Principais autores: Xinyu Wang, Winston Chiu, Hugo Klaassen, Arnaud Marchand, Patrick Chaltin, Johan Neyts, Dirk Jochmans
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-11-01
Serier:Viruses
Fag:
rabies virus
high-throughput screening
drug repurposing
antiviral therapy
Online adgang:https://www.mdpi.com/1999-4915/15/12/2292
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