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A combined approach for single-cell mRNA and intracellular protein expression analysis

Here, the authors present SPARC, a scalable approach for simultaneously measuring mRNA expression levels and targeted intracellular protein levels in single cells. They use SPARC to measure dynamic expression changes in human cells during neuronal differentiation and show that mRNA levels are poor p...

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מידע ביבליוגרפי
Principais autores: Johan Reimegård, Marcel Tarbier, Marcus Danielsson, Jens Schuster, Sathishkumar Baskaran, Styliani Panagiotou, Niklas Dahl, Marc R. Friedländer, Caroline J. Gallant
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Portfolio 2021-05-01
סדרה:Communications Biology
גישה מקוונת:https://doi.org/10.1038/s42003-021-02142-w
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