Vaginally administered PEGylated LIF antagonist blocked embryo implantation and eliminated non-target effects on bone in mice.

Female-controlled contraception/HIV prevention is critical to address health issues associated with gender inequality. Therefore, a contraceptive which can be administered in tandem with a microbicide to inhibit sexually transmitted infections, is desirable. Uterine leukemia inhibitory factor (LIF)...

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Autors principals:	Ellen Menkhorst, Jian-Guo Zhang, Natalie A Sims, Phillip O Morgan, Priscilla Soo, Ingrid J Poulton, Donald Metcalf, Estella Alexandrou, Melissa Gresle, Lois A Salamonsen, Helmut Butzkueven, Nicos A Nicola, Evdokia Dimitriadis
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2011-01-01
Col·lecció:	PLoS ONE
Accés en línia:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21611124/?tool=EBI
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