RNA Polymerase II transcription independent of TBP in murine embryonic stem cells
Transcription by RNA Polymerase II (Pol II) is initiated by the hierarchical assembly of the pre-initiation complex onto promoter DNA. Decades of research have shown that the TATA-box binding protein (TBP) is essential for Pol II loading and initiation. Here, we report instead that acute depletion o...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
eLife Sciences Publications Ltd
2023-03-01
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| Серии: | eLife |
| Предметы: | |
| Online-ссылка: | https://elifesciences.org/articles/83810 |
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