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High-fat and high-sucrose diet impairs female reproduction by altering ovarian transcriptomic and metabolic signatures

Abstract Background Excessive energy intake in modern society has led to an epidemic surge in metabolic diseases, such as obesity and type 2 diabetes, posing profound threats to women’s reproductive health. However, the precise impact and underlying pathogenesis of energy excess on female reproducti...

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Principais autores: Congcong Liu, Yunde Dou, Mengge Zhang, Shan Han, Shourui Hu, Yuxuan Li, Zhiheng Yu, Yue Liu, Xiaofan Liang, Zi-Jiang Chen, Han Zhao, Yuqing Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-02-01
coleção:Journal of Translational Medicine
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Acesso em linha:https://doi.org/10.1186/s12967-024-04952-y
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