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Early pathological changes of coronary microvasculation in heart failure with preserved ejection fraction

Abstract Background The majority of heart failure with preserved ejection fraction (HFpEF) patients present with coronary microvascular dysfunction (CMD). However, it is uncertain whether CMD is a primary factor in ventricular remodeling/diastolic dysfunction and HFpEF, or whether CMD is secondary t...

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Hlavní autoři: Ziyu Guo, Yonghui Xu, Jingjing Xu, Wei Kong, Yanxiang Gao, Jingang Zheng
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2025-11-01
Edice:BMC Cardiovascular Disorders
Témata:
High fat diet (HFD)
N(ω)-nitro-L-arginine methyl-ester (L-NAME)
Heart failure with preserved ejection fraction (HFpEF)
Coronary microvasculation
Pericytes
Coronary microvascular dysfunction
On-line přístup:https://doi.org/10.1186/s12872-025-05354-8
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