Metabolic remodeling and cardiac dysfunction in left ventricular noncompaction: Insights from the MYH7 Q315R model.

Left ventricular noncompaction (LVNC) is a form of cardiomyopathy characterized by excessive trabeculation and a thin compacted myocardial layer. Variants in MYH7, which encodes the β-myosin heavy chain, are among the most commonly identified genetic causes of LVNC. Despite its clinical relevance, t...

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Autores principales:	Shinya Takarada, Yukiko Hata, Keisuke Yaku, Hironori Izumi, Kazuki Fujii, Masaaki Omura, Ichiro Takasaki, Kaori Tsuboi, Mako Okabe, Nariaki Miyao, Hideyuki Nakaoka, Keijiro Ibuki, Sayaka Ozawa, Takashi Nakagawa, Hideyuki Hasegawa, Shojiro Ichimata, Naoki Nishida, Hisashi Mori, Yuko Yanagibashi, Keizo Takao, Fukiko Ichida, Keiichi Hirono
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Public Library of Science (PLoS) 2025-01-01
Colección:	PLoS ONE
Acceso en línea:	https://doi.org/10.1371/journal.pone.0336131
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