COVID-19-associated neuroinflammation and astrocyte death in the brain linked to ORF3a-induced activation of Sur1-mediated ion channels

ABSTRACT The coronavirus disease 2019 (COVID-19) pandemic has disproportionately affected individuals with pre-existing medical conditions, such as neurocognitive disorders. Premorbid neurocognitive conditions compounded by COVID-19 can escalate into COVID-associated neurological complications, lead...

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Hlavní autoři:	Volodymyr Gerzanich, Chenyu Zhang, Jiantao Zhang, Bhargava Teja Sallapalli, Shaokai Pei, Mohamed Nasr, Cigdem Tosun, Yanjin Zhang, Qiyi Tang, J. Marc Simard, Richard Y. Zhao
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2025-09-01
Edice:	mBio
Témata:	COVID-19 SARS-CoV-2 ORF3a reactive astrocytes neuroinflammation and neurotoxicity Sur1-regulated ion channels
On-line přístup:	https://journals.asm.org/doi/10.1128/mbio.02012-25
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